Eosinophilic fasciitis successfully treated with cyclosporine

Clin Rheumatol. 2005 Nov;24(6):634-6. doi: 10.1007/s10067-005-1099-4. Epub 2005 Apr 29.

Abstract

We report on a 45-year-old female who developed eosinophilic fasciitis, characterized by scleroderma-like skin indurations, predominantly on the extremities and chest, with joint contractures and intermittent blood eosinophilia. Histologic examination revealed fibrosis of muscle fascia and eosinophilic infiltration. High-dose systemic corticosteroid therapy was ineffective, but cyclosporine treatment led to remission.

Publication types

  • Case Reports

MeSH terms

  • Cyclosporine / therapeutic use*
  • Eosinophilia / drug therapy*
  • Eosinophilia / pathology
  • Fasciitis / drug therapy*
  • Fasciitis / pathology
  • Female
  • Fibrosis / pathology
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Middle Aged
  • Muscle, Skeletal / pathology
  • Remission Induction
  • Treatment Outcome

Substances

  • Immunosuppressive Agents
  • Cyclosporine