Hypertension management in the elderly has improved: Ontario prescribing trends, 1994 to 2002

Hypertension. 2005 Jun;45(6):1113-8. doi: 10.1161/01.HYP.0000164573.01177.95. Epub 2005 Apr 25.

Abstract

To examine whether the treatment of elderly hypertensives had become more aggressive over the past decade, we evaluated: (1) the frequency of new prescriptions for hypertension treatment, adjusted by age and gender; (2) the frequency with which multiple antihypertensives were prescribed concurrently within 2 years of initial diagnosis; and (3) discontinuation rates for antihypertensive therapy. We linked 4 administrative databases and a province-wide clinical database in Ontario, Canada, to derive a cohort of patients > or =66 years of age who were newly started on an antihypertensive agent between July 1, 1994, and March 31, 2002, without another indication for the agent (all patients were followed for 2 years after their initial antihypertensive prescription). Our cohort consisted of 196 451 people newly started on antihypertensive therapy, 30 433 of whom also had diabetes mellitus. The population-adjusted rate of new antihypertensive prescriptions increased by 30% between 1994 and 2002. Whereas 21% of patients newly diagnosed with hypertension in 1994 were prescribed multiple antihypertensives concurrently within 2 years of diagnosis, this proportion had increased to 40% by 2002 (P<0.0001). In the cohort of patients first prescribed an antihypertensive in 1994, 36% were not taking any antihypertensive within 2 years; only 21% of patients first prescribed an antihypertensive in 2002 had discontinued all therapy within 2 years (P<0.0001). Our data provide evidence that the physician management of hypertension in elderly Canadians became more aggressive between 1994 and 2002.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged*
  • Antihypertensive Agents / therapeutic use*
  • Cohort Studies
  • Databases, Factual
  • Drug Prescriptions / statistics & numerical data
  • Drug Therapy, Combination
  • Female
  • Humans
  • Hypertension / drug therapy*
  • Male
  • Ontario
  • Prospective Studies
  • Quality of Health Care / trends*
  • Time Factors

Substances

  • Antihypertensive Agents