A rapid synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans

J Org Chem. 2005 Apr 29;70(9):3727-9. doi: 10.1021/jo0500941.

Abstract

[reaction: see text] An effective strategy has been developed for the rapid and efficient one-pot synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans from readily available o-nitrotoluenes and aromatic aldehydes. This strategy allows access to a structurally diverse array of products for further manipulation.

MeSH terms

  • Benzofurans / chemical synthesis*
  • Catalysis
  • Combinatorial Chemistry Techniques*
  • Indicators and Reagents
  • Molecular Structure

Substances

  • Benzofurans
  • Indicators and Reagents