Background: Twin pregnancies located in the separate horns of a bicornuate uterus following in vitro fertilization and embryo transfer have been rarely reported.
Case: A 32-year-old woman presented with primary infertility and was diagnosed as having a bicornuate uterus. Because of severe male factor infertility, in vitro fertilization and embryo transfer were recommended. Embryo transfer resulted in a twin pregnancy with a fetus in each horn.
Conclusion: Embryo transfer into separate uterine cavities resulted in a twin pregnancy, with a fetus in each horn, and term delivery. Split embryo transfer into each uterine cavity of an uncorrected bicornuate uterus is a feasible treatment option in selected patients, provided that the couple is counseled about the risks involved.