Individual change in methylphenidate use in a national sample of children aged 2 to 11 years

Can J Psychiatry. 2005 Mar;50(3):144-52. doi: 10.1177/070674370505000303.

Abstract

Objectives: To determine methylphenidate use in children aged 2 to 13 years. To provide age- and sex-specific estimates of methylphenidate initiation and cessation during a 2-year period.

Method: Data from 2 cycles of a Canadian household survey yielded a sample of over 10 000 children aged 2 to 11 years at Cycle 1 who continued to participate at Cycle 2. We used logit modelling to estimate Cycle 2 methylphenidate use, methylphenidate use over a 2-year period, and methylphenidate initiation and cessation from Cycles 1 to 2.

Results: In 1996 and 1997, methylphenidate use ranged from 0.32% to 6.31% among children aged 4 to 13 years. School-aged boys were more likely than girls to use methylphenidate. Odds were greater for boys aged 6 to 7 years than for boys aged 4 to 5 years; they were also greater for boys aged 10 to 11 years than for boys aged 12 to 13 years. Almost 1% of children used methylphenidate at both data cycles. Odds of Cycle 2 methylphenidate use were 135 times greater for children using methylphenidate at Cycle 1, compared with nonusers. Methylphenidate initiation ranged from 0.20% to 3.34%, and school-aged boys had higher initiation rates than girls. Cessation rates ranged from 18% to78%, and there were no statistically significant differences by age and sex.

Conclusions: Methylphenidate prevalence findings are consistent with past studies. We found an age-by-sex interaction on methylphenidate use. We also found both continuity and discontinuity in methylphenidate use.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / drug therapy*
  • Attention Deficit Disorder with Hyperactivity / epidemiology
  • Canada
  • Central Nervous System Stimulants / administration & dosage*
  • Central Nervous System Stimulants / adverse effects
  • Child
  • Child, Preschool
  • Dose-Response Relationship, Drug
  • Drug Utilization / statistics & numerical data
  • Female
  • Follow-Up Studies
  • Health Surveys
  • Humans
  • Logistic Models
  • Male
  • Methylphenidate / administration & dosage*
  • Methylphenidate / adverse effects
  • Prospective Studies
  • Sex Factors

Substances

  • Central Nervous System Stimulants
  • Methylphenidate