Status Dystonicus: study of five cases

Arq Neuropsiquiatr. 2005 Mar;63(1):26-9. doi: 10.1590/s0004-282x2005000100005. Epub 2005 Apr 13.

Abstract

Status Dystonicus (SD) is characterized by generalized muscle contractions in dystonic patients. We report 5 cases of SD, two of which in patients with dystonic cerebral palsy, one in a patient with primary segmental dystonia, one in a patient with Hallervorden-Spatz syndrome and one in a patient with Wilson's disease (WD). Three patients were admitted to an intensive care unit and treated with propofol and midazolam, and two were submitted to neurosurgical procedures (bilateral pallidotomy and bilateral pallidal deep brain stimulation). Triggering factors were identified in three patients as follows: infection, stress-induced and zinc therapy for WD. On follow-up, two patients presented with significant improvement of dystonia, whereas the other three cases the clinical picture ultimately returned to baseline pre-SD condition.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Child
  • Creatine Kinase / blood
  • Dystonic Disorders / blood
  • Dystonic Disorders / drug therapy*
  • Dystonic Disorders / surgery*
  • Electric Stimulation Therapy
  • Humans
  • Male
  • Middle Aged
  • Stereotaxic Techniques
  • Treatment Outcome

Substances

  • Creatine Kinase