Acoustic voice assessment in Parkinson's disease patients submitted to posteroventral pallidotomy

Arq Neuropsiquiatr. 2005 Mar;63(1):20-5. doi: 10.1590/s0004-282x2005000100004. Epub 2005 Apr 13.

Abstract

Long-term complications in levodopa treated Parkinson's disease (PD) patients caused a resurgence of interest in pallidotomy as an option of treatment. However, postoperative complications such as speech disorders can occur.

Purpose: The aim of this study is to evaluate the acoustic voice in PD patients, before and after posteroventral pallidotomy.

Method: Twelve patients with PD were submitted to neurological and voice assessments during the off and on phases, in the pre-operative, 1st and 3rd post-operative months. The patients were evaluated with the UPDRS and the vocal acoustic parameters -- f0, NHR, jitter, PPQ, Shimmer, APQ (using the software MultiSpeech-Kay Elemetrics-3700).

Results: The off phase UPDRS scores revealed a tendency to improvement at the 1st month and the off phase worsened. The shimmer and APQ improved.

Conclusion: This study shows that pallidotomy has little improvement on functional use of communication of PD patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Antiparkinson Agents / adverse effects
  • Antiparkinson Agents / therapeutic use
  • Dysarthria / etiology*
  • Dysarthria / surgery
  • Female
  • Globus Pallidus / surgery*
  • Humans
  • Levodopa / adverse effects
  • Levodopa / therapeutic use
  • Male
  • Middle Aged
  • Parkinson Disease / complications
  • Parkinson Disease / surgery*
  • Severity of Illness Index
  • Speech Acoustics
  • Treatment Outcome
  • Voice Disorders / etiology*
  • Voice Disorders / surgery
  • Voice Quality*

Substances

  • Antiparkinson Agents
  • Levodopa