[Fungal infections in patients with necrotizing pancreatitis: risk-factors, incidence, therapy]

Mycoses. 2005:48 Suppl 1:36-40. doi: 10.1111/j.1439-0507.2005.01108.x.
[Article in German]

Abstract

Haemorraghic necrotizing pancreatitis may lead to a serious disease with multi-organ failure, which is to be treated with intensive care. Patients suffering from infected necrosis are usually operated (necrosectomy). By doing this, it is possible to get a microbiological analysis. The most common virulent species are Enterobacteriaceae. According to the literature, fungal infections appear in 15-30% of the cases. Since 1996, 73 patients were treated surgically in our department. A number of 50 patients (68,5%) developed a fungal infection during the course of the disease. The mortality rate was 62%.

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candida albicans*
  • Candidiasis* / complications
  • Candidiasis* / microbiology
  • Candidiasis* / mortality
  • Candidiasis* / surgery
  • Enterobacteriaceae Infections* / complications
  • Enterobacteriaceae Infections* / microbiology
  • Enterobacteriaceae Infections* / mortality
  • Humans
  • Incidence
  • Pancreatitis, Acute Necrotizing* / complications*
  • Pancreatitis, Acute Necrotizing* / microbiology
  • Pancreatitis, Acute Necrotizing* / mortality
  • Pancreatitis, Acute Necrotizing* / surgery
  • Risk Factors

Substances

  • Antifungal Agents