Efficient synthesis of tribenzohexadehydro[12]annulene and its derivatives in the ionic liquid

Yang Li; Jiyong Zhang; Wenkuan Wang; Qiang Miao; Xuegong She; Xinfu Pan

doi:10.1021/jo047836v

Efficient synthesis of tribenzohexadehydro[12]annulene and its derivatives in the ionic liquid

J Org Chem. 2005 Apr 15;70(8):3285-7. doi: 10.1021/jo047836v.

Authors

Yang Li¹, Jiyong Zhang, Wenkuan Wang, Qiang Miao, Xuegong She, Xinfu Pan

Affiliation

¹ Department of Chemistry, National Key Lab of Applied Organic Chemistry, Lanzhou University, Lanzhou, P.R. China.

PMID: 15822996
DOI: 10.1021/jo047836v

Abstract

A simple and efficient synthesis of tribenzohexadehydro[12]annulene and related derivatives in the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate is described. A Sonogashira coupling reaction is the key step. In this system, the amount of CuI normally used can be reduced so that homocoupling is minimized.