Based on an enquiry made by means of questionnaires sent by post, implemented in 1987 in five health communities of Prague 8, anamnestic data were obtained pertaining to glycoregulation and thyropathies from 5870 respondents. Based on these data the following conclusions were reached: 1. The prevalence of known disorders of glycoregulation, without specification, is in the population of Prague 8 7.98%. The difference between men and women is not significant. The number of disorders increases with age and higher body weight. A positive relationship was confirmed with anamnestic data on the delivery of a heavy foetus in women. Also the importance of a positive thyroid or diabetic family-history was confirmed. Combination of thyroid disease (without more detailed specification) and allergic disease is frequent. Both these relationships are highly significant. Subjects with higher education and subjects born in Prague report disorders of glycoregulation significantly less frequently than other respondents. 2. The prevalence of thyropathies differs significantly in men (3.60%) and women (16.87%). Disorders increase with age but decline again in the higher age brackets. This is particularly marked in women. There is a significant relationship with the family-history and there is frequent combination with impaired glycoregulation. Combination with allergy is also frequent. In subjects with thyropathies the BMI tends towards a scatter to high and low values. No significant relationship with education, place of birth (Prague and non-Prague) nor delivery of heavy foetus was found in women.