Silica-coated nanocomposites of magnetic nanoparticles and quantum dots

Dong Kee Yi; S Tamil Selvan; Su Seong Lee; Georgia C Papaefthymiou; Darshan Kundaliya; Jackie Y Ying

doi:10.1021/ja0428863

Silica-coated nanocomposites of magnetic nanoparticles and quantum dots

J Am Chem Soc. 2005 Apr 13;127(14):4990-1. doi: 10.1021/ja0428863.

Authors

Dong Kee Yi¹, S Tamil Selvan, Su Seong Lee, Georgia C Papaefthymiou, Darshan Kundaliya, Jackie Y Ying

Affiliation

¹ Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669.

PMID: 15810812
DOI: 10.1021/ja0428863

Abstract

Quantum dots (QDs) and magnetic nanoparticles (MPs) are of interest for biological imaging, drug targeting, and bioconjugation because of their unique optoelectronic and magnetic properties, respectively. To provide for water solubility and biocompatibility, QDs and MPs were encapsulated within a silica shell using a reverse microemulsion synthesis. The resulting SiO2/MP-QD nanocomposite particles present a unique combination of magnetic and optical properties. Their nonporous silica shell allows them to be surface modified for bioconjugation in various biomedical applications.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Coated Materials, Biocompatible / chemistry*
Magnetics*
Microscopy, Electron, Transmission
Nanostructures / chemistry*
Quantum Dots*
Silicon Dioxide / chemistry*

Substances

Coated Materials, Biocompatible
Silicon Dioxide