Objective: The aim of this study was to investigate the genotypic profiles of Candida albicans isolates from erosive oral lichen planus (OLP) and non-erosive OLP.
Methods: A total of 112 isolates obtained from healthy control (26), erosive OLP (62) and non-erosive OLP (24) were screened for genotypic profiles by using the randomly amplified polymorphic DNA (RAPD) assay.
Results: RAPD analyses with some random primer reavealed 4 different genotypes among all isolates, and there was significant difference in genotypic constitution between every two groups. Statistically, B and D were the major types in healthy group; A and C were the major types in erosive OLP; A and D were the major types in non-erosive OLP.
Conclusion: Some Candida albicans isolates with special genotypic profiles may contribute to the development and progression of OLP.