Synthesis of regioselectively and uniformly modified maltoheptaose derivatives from cyclomaltoheptaose precursors

Carbohydr Res. 2005 May 2;340(6):1225-31. doi: 10.1016/j.carres.2005.01.021.

Abstract

Heptadeoxy-6(I-VII)-halo, -azido, and hepta-6(I-VII)S-hepta(N-Boc-2-amino)ethyl-6(I-VII)-heptathiomaltoheptaose derivatives were prepared by acetolysis of the corresponding per-C-6-modified beta-cyclodextrin derivatives. The rapid and convenient structural characterisation of all of the modified oligosaccharides by ESIMS is described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbohydrate Sequence
  • Cyclization
  • Glucans / chemical synthesis*
  • Glucans / chemistry*
  • Magnetic Resonance Spectroscopy
  • Spectrometry, Mass, Electrospray Ionization
  • beta-Cyclodextrins / chemistry

Substances

  • Glucans
  • beta-Cyclodextrins
  • maltoheptaose
  • betadex