Brasilibactin A, a cytotoxic compound from actinomycete Nocardia brasiliensis

Masashi Tsuda; Masaaki Yamakawa; Seiko Oka; Yasushi Tanaka; Yasutake Hoshino; Yuzuru Mikami; Ayumi Sato; Hironori Fujiwara; Yasushi Ohizumi; Jun'ichi Kobayashi

doi:10.1021/np0496385

Brasilibactin A, a cytotoxic compound from actinomycete Nocardia brasiliensis

J Nat Prod. 2005 Mar;68(3):462-4. doi: 10.1021/np0496385.

Authors

Masashi Tsuda¹, Masaaki Yamakawa, Seiko Oka, Yasushi Tanaka, Yasutake Hoshino, Yuzuru Mikami, Ayumi Sato, Hironori Fujiwara, Yasushi Ohizumi, Jun'ichi Kobayashi

Affiliation

¹ Graduate School of Pharmaceutical Sciences and Center for Instrumental Analysis, Hokkaido University, Sapporo 060-0812, Japan.

PMID: 15787462
DOI: 10.1021/np0496385

Abstract

A new cytotoxic compound, brasilibactin A (1), has been isolated from the actinomycete Nocardia brasiliensis IFM 0995, and the structure was elucidated on the basis of spectroscopic data and chemical means.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents / chemistry
Antineoplastic Agents / isolation & purification*
Antineoplastic Agents / pharmacology
Drug Screening Assays, Antitumor
Humans
KB Cells
Leukemia L1210
Mice
Nocardia / chemistry*
Stearic Acids / chemistry
Stearic Acids / isolation & purification*
Stearic Acids / pharmacology

Substances

Antineoplastic Agents
Stearic Acids
brasilibactin A