Bilateral testicular tumors in an infertile man previously treated with follicle-stimulating hormones

Urology. 2005 Mar;65(3):592. doi: 10.1016/j.urology.2004.09.017.

Abstract

A 43-year-old infertile man with oligozoospermia and normal serum gonadotropin and cytogenetic findings was treated with follicle-stimulating hormone for 1 year at our institution. Two years later, the patient presented with bilateral palpable testicular tumors. His beta-human chorionic gonadotropin and lactate dehydrogenase levels were elevated. Pathologic examination disclosed a pure seminoma in each testis (pT1N0M0). Adjuvant radiotherapy was administered. The tumors might have been induced by follicle-stimulating hormone treatment. Careful follow-up examination of the testis is necessary in men who have received hormonal treatment for infertility.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Follicle Stimulating Hormone / adverse effects*
  • Humans
  • Infertility, Male / drug therapy*
  • Male
  • Seminoma / chemically induced*
  • Testicular Neoplasms / chemically induced*

Substances

  • Follicle Stimulating Hormone