Anti-inflammatory metabolites from marine sponges

Chem Soc Rev. 2005 Apr;34(4):355-65. doi: 10.1039/b408600g. Epub 2005 Jan 28.

Abstract

Marine sponges are a rich source of biologically active secondary metabolites with novel chemical structures. Eighty four anti-inflammatory compounds have been isolated from marine sponges. This is the first comprehensive review presenting the structures and anti-inflammatory activities of marine sponge metabolites. (100 references).

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents* / chemistry
  • Anti-Inflammatory Agents* / isolation & purification
  • Anti-Inflammatory Agents* / pharmacology
  • Carrageenan / chemistry
  • Edema / chemically induced
  • Edema / prevention & control
  • Humans
  • Molecular Conformation
  • Phospholipases A / antagonists & inhibitors
  • Porifera / chemistry*
  • Superoxides / antagonists & inhibitors

Substances

  • Anti-Inflammatory Agents
  • Superoxides
  • Carrageenan
  • Phospholipases A