[Sporadic cerebral amyloid angiopathy with ischemic leukoencephalopathy and microbleeds. Cause for a rapidly progressive dementia syndrome]

Nervenarzt. 2005 Oct;76(10):1250-4. doi: 10.1007/s00115-005-1884-y.
[Article in German]

Abstract

We describe a 72-year-old patient with rapidly progressive dementia and a complex focal seizure. Magnetic resonance (MR) imaging revealed leukoencephalopathy with the involvement of the U-fibers as well as cortical and subcortical microbleeds. Brain biopsy confirmed the diagnosis of cerebral Abeta amyloid angiopathy (CAA). The presented case illustrates the significance of CAA as a cause of rapidly progressive dementia and leukoencephalopathy and points out the importance of T2-weighted MR imaging in the evaluation of dementia.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Brain Ischemia / complications
  • Brain Ischemia / diagnosis*
  • Cerebral Amyloid Angiopathy / complications
  • Cerebral Amyloid Angiopathy / diagnosis*
  • Cerebral Hemorrhage / complications
  • Cerebral Hemorrhage / diagnosis*
  • Dementia / diagnosis*
  • Dementia / etiology
  • Disease Progression
  • Humans
  • Leukoencephalitis, Acute Hemorrhagic / complications
  • Leukoencephalitis, Acute Hemorrhagic / diagnosis*
  • Male
  • Syndrome