Recently, there is much interest regarding the relationship between periodontal disease and the life style as well as systemic disease including osteoporosis. In addition, there is increasing awareness that dietary calcium intake and other nutrients are important for prevention and management of periodontal disease. In this paper, a cross-sectional study from NHANES III for investigating the association between dietary calcium intake and periodontal disease is introduced, and the management of periodontal disease is proposed from nutritional aspects.