As chemotherapy regimens increase in toxicity and changes in service provision move towards a more ambulatory outpatient basis, patients are often coping with side effects of treatment in isolation. Despite advances in pharmacological control, for some patients nausea and vomiting can be problematic. For some this can develop into anticipatory nausea and vomiting (ANV), which can severely effect the patients physical and psychological well-being. It is well recognised that the giving of realistic and understandable information is paramount to empower patients in their individual coping. A plethora of literature supports the use of Patient Information Leaflets as a means to educate and empower patients within their treatment trajectory. This paper discusses the authors' experiences in developing a Patient Information Leaflet, designed to assist breast cancer patients in understanding and coping with the symptoms of ANV. The patient's needs were sought to add clarity to the development and design of the leaflet. The authors conclude that developing a Patient Information Leaflet was a major undertaking in terms of time and resources.