Absence of human papillomavirus in esophageal carcinomas from southwestern Kenya

Dis Esophagus. 2005;18(1):28-30. doi: 10.1111/j.1442-2050.2005.00452.x.

Abstract

Esophageal squamous cell cancer is highly prevalent in south-western Kenya. The role of human papillomavirus (HPV) in esophageal cancers from this region was evaluated. Biopsies of 29 esophageal squamous cell cancers were assayed for HPV DNA sequences by reverse line blot polymerase chain reaction, using 27 HPV type-specific probes. Viral sequences were found in none of the specimens. These results suggest the HPV is unlikely to be an etiologic factor for esophageal squamous cell cancers in this region.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • DNA, Viral / isolation & purification*
  • Esophageal Neoplasms / diagnosis
  • Esophageal Neoplasms / etiology*
  • Esophagoscopy
  • Female
  • Humans
  • Kenya
  • Male
  • Middle Aged
  • Neoplasms, Squamous Cell / diagnosis
  • Neoplasms, Squamous Cell / etiology*
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / complications*
  • Polymerase Chain Reaction
  • Prospective Studies

Substances

  • DNA, Viral