MR findings in eosinophilic infiltration of the liver

J Comput Assist Tomogr. 2005 Mar-Apr;29(2):191-4. doi: 10.1097/01.rct.0000159106.93063.6b.

Abstract

Objective: This study describes the findings of magnetic resonance imaging (MRI) of focal eosinophilic infiltration of the liver.

Methods: Contrast-enhanced MR images of 8 patients with focal hepatic eosinophilic infiltration were reviewed retrospectively. We evaluated the signal intensity of focal lesions in T1-weighted and T2-weighted images and the pattern of enhancement in a dynamic contrast study.

Results: A total 22 focal hepatic lesions were observed; the lesions were isointense (55%) or hypointense (45%) on T1-weighted images and isointense (14%) or hyperintense (86%) on T2-weighted images. The arterial phase of the contrast study revealed 11 hyperintense lesions (50%). During the portal and delayed phases, 18 (82%) and 17 lesions (77%) were hyperintense, respectively.

Conclusion: The focal eosinophilic infiltrations showed homogeneous enhancement in the portal and delayed phases in the dynamic contrast MR study. These findings should help to distinguish focal eosinophilic infiltration, especially from metastasis in patients with malignancy.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Biopsy
  • Clonorchiasis / diagnosis
  • Clonorchiasis / pathology
  • Contrast Media / administration & dosage
  • Diagnosis, Differential
  • Eosinophilia / diagnosis*
  • Eosinophilia / etiology
  • Female
  • Gadolinium DTPA
  • Humans
  • Hypereosinophilic Syndrome / diagnosis
  • Hypereosinophilic Syndrome / pathology
  • Image Enhancement*
  • Image Processing, Computer-Assisted*
  • Liver / pathology
  • Liver Diseases / diagnosis*
  • Liver Diseases / etiology
  • Liver Diseases, Parasitic / diagnosis
  • Liver Diseases, Parasitic / pathology
  • Liver Neoplasms / diagnosis
  • Liver Neoplasms / secondary
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / pathology
  • Tomography, X-Ray Computed

Substances

  • Contrast Media
  • Gadolinium DTPA