Abstract
L- and D-stereoisomers of amicetose were generated by combining sugar biosynthesis genes from four different antibiotic gene clusters and both sugars were transferred to the elloramycin aglycone by the sugar flexible ElmGT glycosyltransferase.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cloning, Molecular
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Enzymes / genetics
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Hexoses / biosynthesis*
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Hexoses / genetics*
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Molecular Structure
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Naphthacenes / chemistry*
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Naphthacenes / classification
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Naphthacenes / pharmacology
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Plasmids / genetics
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Plasmids / metabolism
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Stereoisomerism
Substances
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Enzymes
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Hexoses
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Naphthacenes
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5838 DNI
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amicetose