Freestanding implants with mandibular overdentures are used frequently after 3 months' healing time. Immediate full loading may be applied to this approach if sufficient primary stability is provided. The present study evaluates the success rate of two single-standing interforaminal implants stabilized with cortical satellite implants and loaded immediately with overdentures. Twenty patients (five male and 15 female; age, 45-87 years) received two single-standing titanium screw implants (Semados, Bego, Bremen, Germany). All implants were stabilized during healing time with cortical satellite implants (2.0-mm bone screws; Medartis, Basel, Switzerland) via individual connectors attached to the implant abutment subgingivally. Mandibular overdentures were incorporated immediately after surgery using ball attachments as retentive elements. The patients were under no restrictions concerning diet and loading. The satellite implants were removed after 3 months. All implants were osseointegrated after 10 months' mean observation time. The mean Periotest value was -4.9, and the mean marginal bone loss was 0.7 mm. No dropouts were observed, and 19 of 20 patients would recommend the treatment to a close friend. Preliminary follow-up data indicate that cortical stabilization of two anterior mandibular implants with satellite implants leads to osseointegration of the implants under immediate load conditions with an overdenture. This concept contributes to reduction of prosthetic treatment costs and permits immediate enhancement of masticatory function.