A multicenter retrospective statistical study was carried out to evaluate whether functional prosthetic loading of an implant 8 weeks after surgical insertion is acceptable clinically. Based on studies in vitro, which confirm that the fastest and best quality bone healing occurs around implants with surface treatment specifically after sanding with Al2O3 and subsequent passivity, this knowledge was applied to clinics. Four hundred and fifteen implants were inserted in 128 patients regardless of the pathology they presented and the quantity or quality of the area of the bone to be treated. Thus, all patients were included in the study independent of their physiological and pathological characteristics. The area of implant insertion, the type of prosthesis used, and the rate of success or survival of implants with bone resorption or mucositis were evaluated. With respect to the total number of implants loaded at 8 weeks, the rate of success for completely successful implants was 95.38%, and the rate of success of both partially and completely successful implants was 99.75%. Functional prosthetic loading at 8 weeks is an appropriate procedure, providing that technology of the implant surface guarantees, once the time has passed, that the osteointegration is achieved and capable of holding loading.