Abstract
A supramolecular assembly of phospholipid-polymerized diacetylene vesicles functionalized with glycolipid can provide a molecular recognition function. The Escherichia coli-glycolipid binding event leads to a visible color change from blue to red, readily seen with the naked eye and quantified by absorption spectroscopy. The biosensor signal is amplified through a suitable increase of phospholipid content in the mixed lipid vesicles and pH of aqueous solutions.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetylene / analogs & derivatives
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Acetylene / chemistry
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Bacteriological Techniques / methods
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Biosensing Techniques / methods*
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Colorimetry / methods
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Dimyristoylphosphatidylcholine / chemistry
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Escherichia coli / isolation & purification*
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Fatty Acids, Unsaturated / chemistry
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Glycolipids / chemistry*
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Hydrogen-Ion Concentration
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Liposomes / chemistry*
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Mannose / chemistry
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Microscopy, Electron, Transmission
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Oligosaccharides / chemistry
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Photochemistry
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Polyacetylene Polymer
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Polymers / chemistry
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Polyynes
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Spectrophotometry
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Ultraviolet Rays
Substances
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10, 12-pentacosadiynoic acid
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Fatty Acids, Unsaturated
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Glycolipids
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Liposomes
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Oligosaccharides
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Polyacetylene Polymer
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Polymers
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Polyynes
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polydiacetylene
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Acetylene
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Mannose
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Dimyristoylphosphatidylcholine