Hydrogen-bonding and C-H...pi interactions in 7-hydroxy-3-methoxy-4-methyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidin-1(9H)-one

Acta Crystallogr C. 2005 Mar;61(Pt 3):o158-60. doi: 10.1107/S010827010500079X. Epub 2005 Feb 19.

Abstract

In the title compound, C10H14N2O3, a pyrimidine ring is fused with a piperidine ring. The pyrimidine ring is planar, whereas the piperidine ring adopts a half-chair conformation. The molecules of the title compound are connected via O-H...O intermolecular hydrogen bonds into infinite zigzag chains. The pyrimidine ring is involved in three C-H...pi interactions, which link the hydrogen-bonded chains into a three-dimensional framework.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antiviral Agents / chemistry
  • Crystallography, X-Ray
  • Hydrogen Bonding
  • Molecular Structure
  • Piperidines / chemistry*
  • Pyrimidinones / chemistry*

Substances

  • Antineoplastic Agents
  • Antiviral Agents
  • Piperidines
  • Pyrimidinones