Evaluation of the estrogenic activity of Leguminosae plants

Biol Pharm Bull. 2005 Mar;28(3):538-40. doi: 10.1248/bpb.28.538.

Abstract

The plant extracts of the Leguminosae family were screened for their estrogenic activity with the Ishikawa cell system. Of the tested plants, Desmodium oxyphyllum, Dunbaria villosa, Kummerowia striata, Lespedeza bicolor, Maackia amurensis, Maackia fauriei, Pueraria thunbergiana, and Sophora flavescens were highly estrogenic with EC50 values of less than 10 microg/ml.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Drug Evaluation, Preclinical / methods
  • Fabaceae*
  • Humans
  • Phytoestrogens / isolation & purification
  • Phytoestrogens / pharmacology*
  • Phytoestrogens / toxicity
  • Plant Components, Aerial
  • Plant Extracts / isolation & purification
  • Plant Extracts / pharmacology

Substances

  • Phytoestrogens
  • Plant Extracts