In conclusion, in the course of patients with advanced liver disease there are several indications for institution of intravenous albumin. These include: a) enhancement of diuretic effect on mobilization of ascites fluid, b) prevention of post-paracentesis circulatory dysfunction after total/large volume paracentesis, c) prevention of hepatorenal syndrome in patients affected with SBP, and d) administration of albumin in combination with vasoconstrictor drugs as the only effective therapy for hepatorenal syndrome. Albumin is relatively inexpensive and can be given in an outpatient setting.