A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation

PLoS Biol. 2005 Feb;3(2):e76. doi: 10.1371/journal.pbio.0030076.

Abstract

Studies of the transcriptional transactivator (Tat), a key regulatory protein of HIV, have yielded insight into the control of eukaryotic transcription

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Gene Products, tat / genetics*
  • HIV / enzymology
  • HIV / genetics*
  • Models, Biological
  • Molecular Biology / trends
  • RNA Polymerase II / genetics
  • RNA Polymerase II / metabolism
  • Transcription, Genetic*
  • Transcriptional Elongation Factors / genetics
  • tat Gene Products, Human Immunodeficiency Virus

Substances

  • Gene Products, tat
  • Transcriptional Elongation Factors
  • tat Gene Products, Human Immunodeficiency Virus
  • RNA Polymerase II