Abstract
The effects of Gastrodia elata on preventing decrepitude and advancing memory are closely associated with its neuroprotective activity. Previous researches proved that G. elata, its active components and preparations played a neuroprotective role by affecting the excitotoxicity, nitric monoxide (NO) system, neuroglia, biomembrane, oxidative neurotoxicity, apoptosis et al. Recent researches also suggest that reducing energy metabolism impairment, anti-inflammatory and immune modulating function may be new research targets of neuroprotective mechanism of G. elata.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Antioxidants / pharmacology*
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Apoptosis / drug effects
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Calcium / metabolism
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Drugs, Chinese Herbal / isolation & purification
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Drugs, Chinese Herbal / pharmacology*
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Excitatory Amino Acids / antagonists & inhibitors
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Gastrodia* / chemistry
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Humans
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Neuroprotective Agents / pharmacology*
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Nitric Oxide / metabolism
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Nitric Oxide Synthase / metabolism
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Plants, Medicinal / chemistry
Substances
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Antioxidants
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Drugs, Chinese Herbal
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Excitatory Amino Acids
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Neuroprotective Agents
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Nitric Oxide
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Nitric Oxide Synthase
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Calcium