Intercellular communications induced by random fluctuations

Genome Inform. 2004;15(2):223-33.

Abstract

This paper investigates a general coupled noisy system for a cell-cell communication in a multi-cell system. The main conclusion is that appropriate noise intensity and coupling strength are capable of driving the coupled system to synchrony, which may be exploited by biological organisms to actively facilitate mutual communication. A multi-cell system with a synthetic gene network with both noises and delays is adopted to demonstrate the effect of noises on cellular communication.

MeSH terms

  • Adaptation, Physiological / physiology
  • Cell Communication / physiology*
  • Computer Simulation
  • Gene Expression Regulation / physiology*
  • Models, Biological*
  • Models, Statistical
  • Signal Transduction / physiology*
  • Stochastic Processes*