Objective: To study the relationship between the adipose tissues and cutaneous morphogenesis on wound healing.
Methods: Adipose tissues' participation in regulation of food intake, energy expenditure, fuel metabolism, and a variety of other physiological processes was reviewed in the latest literature. The wound healing was regulated by endocrine, paracrine, and adipocyte-derived molecules.
Results: Several factors secreted by adipose tissues (leptin, cytokines, growth factors, lipids, metallothioneins, ect) regulated wound healing.
Conclusion: Adipose tissues may play a vital role in the process of wound healing. Further understanding of the complex interaction between adipose cells and cutaneous morphogenesis is essential to explore the mechanism of wound healing.