Sodium transport in airway epithelium correlates with lung compliance in healthy newborn infants

J Pediatr. 2005 Feb;146(2):273-6. doi: 10.1016/j.jpeds.2004.09.024.

Abstract

To study the relation between sodium transport in airway epithelium and postnatal pulmonary adaptation, we measured nasal potential difference at 1 to 4 hours and lung compliance at 21 to 48 hours after birth in 20 healthy infants. Sodium transport correlated with lung compliance ( r 2 = 0.40, P < .003). Airway sodium transport plays a role in postnatal pulmonary adaptation.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Epithelial Cells / metabolism
  • Female
  • Humans
  • Infant, Newborn
  • Ion Transport
  • Lung Compliance / physiology*
  • Male
  • Respiratory Mucosa / metabolism*
  • Sodium / metabolism*
  • Sodium / pharmacokinetics

Substances

  • Sodium