Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract

Antimicrob Agents Chemother. 2005 Feb;49(2):798-800. doi: 10.1128/AAC.49.2.798-800.2005.

Abstract

Among 63 patients enrolled in a prospective cohort study of gut colonization with fluoroquinolone-resistant Escherichia coli, the sensitivity of perirectal swab compared to stool sample was 90% (95% confidence interval [CI], 70 to 99%) and the specificity was 100% (95% CI, 91 to 100%). For rectal swab, the sensitivity was 90% (95% CI, 68 to 99%) and the specificity was 100% (95% CI, 91 to 100%).

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / pharmacology*
  • Cohort Studies
  • Cross-Sectional Studies
  • Digestive System / microbiology*
  • Drug Resistance, Bacterial*
  • Escherichia coli / drug effects*
  • Feces / microbiology*
  • Female
  • Fluoroquinolones / pharmacology*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Rectum / microbiology*
  • Reproducibility of Results

Substances

  • Anti-Bacterial Agents
  • Fluoroquinolones