In three experiments, we examined how readers learn and generalize new pronunciations for vowel graphemes. Children ages 6 1/2 to 9 (n = 97) and college students (n = 21) were taught a nonword that included a novel vowel pronunciation in the middle position (e.g., zuop is pronounced /zup/). They were then asked to pronounce other nonwords that contained the same vowel grapheme. Participants were more likely to use the taught pronunciation when the target item and the training item shared a consonant as well as a vowel than when they shared only the vowel. The new pronunciation was not significantly more likely to appear when the target shared the vowel and final consonant (rime) of the training stimulus than when it shared the initial consonant and vowel. We discuss implications for views of reading and its development.