Solid phase synthesis of biohybrid block copolymers

Chem Commun (Camb). 2005 Feb 7:(5):602-4. doi: 10.1039/b413973a. Epub 2004 Dec 8.

Abstract

A new versatile route to synthesise biohybrid block copolymers is presented in which an amine terminated polymer is attached to an aldehyde functionalised resin, from which in subsequent steps the desired peptide can be grown using standard procedures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Amines / chemistry
  • Biopolymers / chemistry*
  • Combinatorial Chemistry Techniques / methods*
  • Molecular Structure
  • Peptides / chemical synthesis*
  • Peptides / chemistry*
  • Resins, Synthetic / chemistry

Substances

  • Aldehydes
  • Amines
  • Biopolymers
  • Peptides
  • Resins, Synthetic