Pattern of expression of the podocalyxin gene in the mouse brain during development

Nathalia Vitureira; Kelly McNagny; Eduardo Soriano; Ferran Burgaya

doi:10.1016/j.modgep.2004.10.002

Pattern of expression of the podocalyxin gene in the mouse brain during development

Gene Expr Patterns. 2005 Feb;5(3):349-54. doi: 10.1016/j.modgep.2004.10.002.

Authors

Nathalia Vitureira¹, Kelly McNagny, Eduardo Soriano, Ferran Burgaya

Affiliation

¹ IRBB/PCB, Barcelona Science Park and Department of Cell Biology, University of Barcelona, Josep Samitier 1-5, Barcelona E-08028, Spain.

PMID: 15661640
DOI: 10.1016/j.modgep.2004.10.002

Abstract

We studied the expression pattern of the major renal protein Podocalyxin during the development of mouse brain using in situ hybridization. Podocalyxin mRNA was widely expressed at least from E14, the first age we studied, and expression remained high until adulthood. The highest levels of expression were postnatal. Podocalyxin expression was particularly elevated in the cortical plate, the hippocampus and cerebellum, and in several basal forebrain nuclei.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blotting, Northern
Brain / embryology
Brain / growth & development*
Brain / metabolism*
Cerebellum / growth & development
Cerebellum / metabolism
Gene Expression Regulation, Developmental
Hippocampus / growth & development
Hippocampus / metabolism
In Situ Hybridization
Mice
Prosencephalon / growth & development
Prosencephalon / metabolism
Sialoglycoproteins / biosynthesis*
Sialoglycoproteins / genetics*

Substances

Sialoglycoproteins
podocalyxin