Colorectal cancer in patients over 70 years of age: determinants of outcome

Tech Coloproctol. 2004 Nov:8 Suppl 1:s112-5. doi: 10.1007/s10151-004-0128-7.

Abstract

Background: The aim of this study was to evaluate operative risk factors, the mortality, morbidity and survival in old patients with colorectal cancer.

Methods: From 1160 patients with colorectal cancer, 398 patients aged 70 years or older, from 1970 to 2000, were followed-up. Dukes' classification, differentiation, sex, anatomical site and survival were compared with patients <70 years old.

Results: Long-term results have been proved to be similar both in young and old patients. Relative survival rate for patients aged 70-95 (70.5%) were similar to those for patients less than 70 years old (71.6%) and also comparable between male (72.3%) and female (68%) patients.

Conclusions: Elderly patients have a lower capacity to react to postoperative complications, but the relative survival is similar to younger patients. Advanced age alone should not be used as a criterion to deny surgery for colorectal cancer.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Cause of Death*
  • Chemotherapy, Adjuvant
  • Colectomy / methods
  • Colorectal Neoplasms / mortality*
  • Colorectal Neoplasms / pathology
  • Colorectal Neoplasms / therapy*
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Perioperative Care
  • Postoperative Complications / mortality*
  • Predictive Value of Tests
  • Probability
  • Proportional Hazards Models
  • Radiotherapy, Adjuvant
  • Risk Assessment
  • Survival Analysis
  • Treatment Outcome