Evolving treatment strategies for myeloma

Br J Cancer. 2005 Jan 31;92(2):217-21. doi: 10.1038/sj.bjc.6602341.

Abstract

In this article, we will discuss how treatment strategies for myeloma have evolved and outline the challenges now faced following the introduction of a number of novel active agents. In particular, we will focus on how achieving a maximum response and maintaining such responses is becoming a key therapeutic strategy and how novel agents can be used to achieve this in the context of current strategies such as autologous transplantation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols
  • Boronic Acids / therapeutic use
  • Bortezomib
  • Clinical Trials as Topic
  • Humans
  • Multiple Myeloma / drug therapy*
  • Protease Inhibitors / therapeutic use
  • Pyrazines / therapeutic use
  • Thalidomide / therapeutic use

Substances

  • Angiogenesis Inhibitors
  • Boronic Acids
  • Protease Inhibitors
  • Pyrazines
  • Thalidomide
  • Bortezomib