Two new phloroglucinol glycosides, lysidisides A and B, and two new flavanol ramifycations, lysidicichin and mopanolside, together with (+)-mopanol, polydatin and E-resveratrol 3-O-beta-D-xylopyranoside were isolated from the EtOAc extract of the roots of Lysidice rhodostega. The structures of the new compounds were elucidated on the basis of chemical and spectral evidence. Lysidisides A and B, (+)-mopanol and polydatin inhibited phenylepherine (Phe)-induced vasoconstriction in the rat aortic rings in the presences of indomethacin (Indo) and Nomega-L-nitroarginine (L-NA).