Cytotoxic iridoid aldehydes from Taiwanese Viburnum luzonicum

Chem Pharm Bull (Tokyo). 2005 Jan;53(1):125-7. doi: 10.1248/cpb.53.125.

Abstract

Four new iridoid aldehydes bearing (E)- or (Z)-p-coumaroyl group, luzonial A (1), luzonial B (2), luzonidial A (3), and luzonidial B (4), were isolated from a methanol extract of the dried leaves of Viburnum luzonicum collected in Kaoshiung, Taiwan and their structures were elucidated by analysis of spectroscopic data. Compounds 1-3 exhibited moderate inhibitory activity against HeLa S3 cancer cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Aldehydes / isolation & purification
  • Aldehydes / toxicity*
  • Cell Proliferation / drug effects
  • HeLa Cells
  • Humans
  • Iridoids / chemistry
  • Iridoids / isolation & purification
  • Iridoids / toxicity*
  • Plant Extracts / chemistry
  • Plant Extracts / isolation & purification
  • Plant Extracts / toxicity*
  • Plant Leaves
  • Taiwan
  • Viburnum*

Substances

  • Aldehydes
  • Iridoids
  • Plant Extracts