2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica

Melanie Muller; Maureenx Byres; Marcel Jaspars; Yashodharan Kumarasamy; Moira Middleton; Lutfun Nahar; Mohammad Shoeb; Satyajit D Sarker

2D NMR spectroscopic analyses of archangelicin from the seeds of Angelica archangelica

Acta Pharm. 2004 Dec;54(4):277-85.

Authors

Melanie Muller¹, Maureenx Byres, Marcel Jaspars, Yashodharan Kumarasamy, Moira Middleton, Lutfun Nahar, Mohammad Shoeb, Satyajit D Sarker

Affiliation

¹ Phytopharmaceutical Research Laboratory, School of Pharmacy, The Robert Gordon University, Schoolhill, Aberdeen AB10 1FR, Scotland, UK.

PMID: 15634612

Abstract

A total of six coumarins, bergapten (1), xanthotoxin (2), imperatorin (3), isoimperatorin (4), phellopterin (5) and archangelicin (6), have been isolated from an n-hexane extract of the seeds of Angelica archangelica. The results of comprehensive 2D NMR analyses of archangelicin are discussed.

MeSH terms

5-Methoxypsoralen
Angelica archangelica / chemistry*
Coumarins / analysis*
Furocoumarins / analysis*
Methoxsalen / analogs & derivatives*
Methoxsalen / analysis
Nuclear Magnetic Resonance, Biomolecular*
Plant Proteins / analysis*
Plants, Medicinal / chemistry*
Protein Conformation
Protein Folding
Seeds / chemistry*

Substances

Coumarins
Furocoumarins
Plant Proteins
isoimperatorin
phellopterin
5-Methoxypsoralen
archangelicin
imperatorin
Methoxsalen