Abstract
Fungal endocarditis, in particular due to Candida species, requires medical and surgical treatment and amphotericin B is the drug of choice. Caspofungin is an echinocandin very effective against Candida and Aspergillus. We present a patient with Candida tropicalis endocarditis, fluconazol resistant, treated with caspofungin, on a compassional basis as a result of adverse effects with amphotericin B. The patient had a microbiological response.
MeSH terms
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Aged
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Antifungal Agents / therapeutic use*
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Candida tropicalis / drug effects*
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Candidiasis / complications
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Candidiasis / drug therapy*
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Caspofungin
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Drug Resistance, Fungal
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Echinocandins
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Endocarditis / drug therapy*
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Endocarditis / microbiology
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Fatal Outcome
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Fluconazole / therapeutic use*
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Humans
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Lipopeptides
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Male
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Peptides, Cyclic / therapeutic use*
Substances
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Antifungal Agents
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Echinocandins
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Lipopeptides
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Peptides, Cyclic
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Fluconazole
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Caspofungin