Two new alkaloids from the rhizome of Polygonatum sibiricum

J Asian Nat Prod Res. 2005 Apr;7(2):127-30. doi: 10.1080/10286020310001625157.

Abstract

Two new alkaloids named polygonatine A (1) and polygonatine B (2) have been isolated from the rhizome of Polygonatum sibiricum Redoute (Liliaceae). By spectral data (IR, UV, MS, 1D and 2D NMR) and chemical evidence, their structures were elucidated as 3-hydroxymethyl-5,6,7,8-tetrahydroindolizin-8-one (1) and 3-ethoxymethyl-5,6,7,8-tetrahydroindolizin-8-one (2).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkaloids / chemistry
  • Alkaloids / isolation & purification*
  • Chromatography, Thin Layer
  • Drugs, Chinese Herbal / chemistry
  • Indolizines / chemistry
  • Indolizines / isolation & purification*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Polygonatum / chemistry*
  • Rhizome / chemistry
  • Spectrometry, Mass, Fast Atom Bombardment
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet

Substances

  • Alkaloids
  • Drugs, Chinese Herbal
  • Indolizines