Spindle regulation: Mps1 flies into new areas

Curr Biol. 2004 Dec 29;14(24):R1058-60. doi: 10.1016/j.cub.2004.11.047.

Abstract

Analysis of a mutation in the Drosophila Mps1 ortholog further demonstrates the universality of Mps1 function in the spindle checkpoint, but suggests Mps1 function in centrosome duplication might not be so conserved. The work also contributes new additions to a list of Mps1 functions that continues to grow with each new study.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Animals
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / physiology*
  • Cell Division / genetics
  • Centrosome / physiology
  • Chromosome Segregation / physiology*
  • Drosophila
  • Genes, cdc / physiology*
  • Mutation / genetics
  • Protein Kinases / genetics
  • Protein Kinases / physiology*
  • Spindle Apparatus / physiology*

Substances

  • Cell Cycle Proteins
  • Protein Kinases