Triterpenes from Maesopsis eminii

Patrice Aimé Fokou; Hans-Georg Stammler; Beate Neumann; Thomas Huber; David Lontsi; Hilaire V Kemami Wangun; Norbert Sewald

doi:10.1021/np0497548

Triterpenes from Maesopsis eminii

J Nat Prod. 2004 Dec;67(12):2124-6. doi: 10.1021/np0497548.

Authors

Patrice Aimé Fokou¹, Hans-Georg Stammler, Beate Neumann, Thomas Huber, David Lontsi, Hilaire V Kemami Wangun, Norbert Sewald

Affiliation

¹ Department of Chemistry, University of Bielefeld, PO Box 100131, 33501 Bielefeld, Germany.

PMID: 15620269
DOI: 10.1021/np0497548

Abstract

Two pentacyclic triterpenes, 1alpha,3beta-dihydroxybauer-7-en-28-oic acid (1) and 3beta-hydroxybauer-7-en-28-oic acid (2), together with sitosterol-3-beta-O-d-glucopyranoside and stigmasterol have been isolated from the bark of the plant Maesopsis eminii. Their structures have been elucidated by spectroscopic methods. One of the triterpenes (1) is new, and its structure was confirmed by X-ray crystallographic analysis. This new triterpene displayed moderate antibacterial activity against Bacillus subtilis ATCC 6633.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification*
Anti-Bacterial Agents / pharmacology
Bacillus subtilis / drug effects
Cameroon
Crystallography, X-Ray
Molecular Conformation
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Bark / chemistry
Plants, Medicinal / chemistry*
Rhamnaceae / chemistry*
Triterpenes / chemistry
Triterpenes / isolation & purification*
Triterpenes / pharmacology

Substances

1alpha,3beta-dihydroxybauer-7-en-28-oic acid
3beta-hydroxybauer-7-en-28-oic acid
Anti-Bacterial Agents
Triterpenes