[Safety assessment of GM yeast feed additive with cecropin CAD gene]

Wei Sheng Yan Jiu. 2004 Sep;33(5):565-9.
[Article in Chinese]

Abstract

Objective: To evaluate the safety of GM yeast feed additive with cecropin CAD and to study and set up a model of Safety assessment for GM feed and detecting method.

Methods: To ensure the safety of the GM products, it has been done that to detect and value the safety of receptor organisms and expression products of extrinsic gene, the genetic stability of biologic properties of genomic modified yeast feed and condition of transfer and cumulation of anti-bacterial peptide and its products in circumstance and the feeded animals.

Result and conclusion: The receptor animals and expression products of extrinic gene are safe, and the genomic modified products have steady genetic characters. The cectopin CAD neither cumulates in feeded animal nor releases into environment. The genomic modified feed additive is safe.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Feed / toxicity*
  • Animals
  • Antimicrobial Cationic Peptides / genetics
  • Antimicrobial Cationic Peptides / metabolism*
  • Chickens
  • Decapoda
  • Food Additives / toxicity*
  • Food, Genetically Modified / toxicity*
  • Mice
  • Organisms, Genetically Modified*
  • Risk Assessment
  • Safety
  • Swine
  • Toxicity Tests
  • Yeasts / genetics*
  • Yeasts / metabolism

Substances

  • Antimicrobial Cationic Peptides
  • Food Additives