A novel photoadduct of 4,5',8-trimethylpsoralen and adenosine

M H Yun; S J Choi; S C Shim

doi:10.1111/j.1751-1097.1992.tb04261.x

A novel photoadduct of 4,5',8-trimethylpsoralen and adenosine

Photochem Photobiol. 1992 Mar;55(3):457-60. doi: 10.1111/j.1751-1097.1992.tb04261.x.

Authors

M H Yun¹, S J Choi, S C Shim

Affiliation

¹ Department of Chemistry, Korea Advanced Institute of Science and Technology, Seoul.

PMID: 1561242
DOI: 10.1111/j.1751-1097.1992.tb04261.x

Abstract

A novel photoadduct of 4,5',8-trimethylpsoralen (TMP) and adenosine was isolated and purified by reverse-phase liquid chromatography. The structure of the photoproduct was determined by various spectral methods and found to be a TMP-adenosine 1:1 adduct resulting from the covalent bond formation between the carbon C(4) of TMP and ribose 4'-carbon of adenosine.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenosine / chemistry
Adenosine / radiation effects*
Molecular Structure
Photochemistry
Radiation-Sensitizing Agents / chemical synthesis
Radiation-Sensitizing Agents / chemistry
Trioxsalen / chemical synthesis
Trioxsalen / chemistry
Trioxsalen / radiation effects*

Substances

Radiation-Sensitizing Agents
Adenosine
Trioxsalen