Local utilization of metacresolsulfonic acid combined with streptomycin in the treatment of actinomycosis

Ann N Y Acad Sci. 2004 Oct:1026:273-6. doi: 10.1196/annals.1307.042.

Abstract

The effectiveness of combining metacresolsufonic acid with streptomycin in the treatment of actinomycosis, diagnosed either clinically or in the laboratory, was evaluated in 12 bovines and 2 equines. Eighty-seven percent of treated animals were considered clinically cured and did not show any signs of relapse after a six-month follow-up period. Therapeutic diagnosis by clinical observation was the procedure of choice when it was not possible to obtain laboratory diagnosis.

Publication types

  • Clinical Trial

MeSH terms

  • Actinomycosis / drug therapy*
  • Animals
  • Antibiotics, Antineoplastic / administration & dosage
  • Antibiotics, Antineoplastic / therapeutic use*
  • Cattle
  • Cattle Diseases / drug therapy*
  • Cresols / administration & dosage
  • Cresols / therapeutic use*
  • Drug Combinations
  • Drug Therapy, Combination
  • Formaldehyde / administration & dosage
  • Formaldehyde / therapeutic use*
  • Horse Diseases / drug therapy*
  • Horses
  • Streptozocin / administration & dosage
  • Streptozocin / therapeutic use*
  • Treatment Outcome

Substances

  • Antibiotics, Antineoplastic
  • Cresols
  • Drug Combinations
  • Formaldehyde
  • Streptozocin
  • formaldehyde, meta-cresolsulfonic acid drug combination