Gestrinone in the treatment of uterine leiomyomata: effects on uterine blood supply

Fertil Steril. 2004 Dec;82(6):1694-6. doi: 10.1016/j.fertnstert.2004.08.004.

Abstract

Gestrinone has been shown to reduce uterine volume and stop bleeding in women with uterine leiomyomata. In the present study, we demonstrated a reduction in the volume of uterine myomas and in the uterine artery blood perfusion over a 6-month period of gestrinone administration in premenopausal women.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Estrogen Antagonists / therapeutic use*
  • Female
  • Gestrinone / therapeutic use*
  • Humans
  • Leiomyomatosis / blood supply*
  • Leiomyomatosis / diagnostic imaging
  • Leiomyomatosis / drug therapy*
  • Premenopause
  • Regional Blood Flow / drug effects
  • Time Factors
  • Treatment Outcome
  • Ultrasonography
  • Uterine Neoplasms / blood supply*
  • Uterine Neoplasms / diagnostic imaging
  • Uterine Neoplasms / drug therapy*

Substances

  • Estrogen Antagonists
  • Gestrinone